Tutorial - Cardiostimulatory Drugs

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1. What are the effects of cardiostimulatory drugs on heart rate, electrical conduction within the heart, stroke volume, cardiac output and myocardial oxygen demand?  click here
2. For what cardiovascular disorders are cardiostimulatory drugs use and why are they effective for each of these conditions?  click here
3. What mechanistic classes of drugs are cardiostimulatory?  click here
4. Which mechanistic class of cardiostimulatory drugs is sympathomimetic?  click here
5. How do beta-agonists affect heart rate, conduction velocity, mechanical function and myocardial oxygen demand? What signal transduction pathways are involved in these effects?  click here
6. What beta-agonists that are used in treating acute heart failure and circulatory shock?  Describe their pharmacology.  click here
7. How do digitalis compounds increase cardiac inotropy in heart failure patients?  click here
8. What are the pharmacokinetics for digoxin and digitoxin and how do these properties affect how these drugs are given?  click here
9. What are some important side-effects and drug interactions for digitalis compounds?  click here
10. What is the mechanism by which phosphodiesterase inhibitors stimulate the heart in heart failure patients?  click here
11. What are some important side-effects of phosphodiesterase inhibitors?  click here

Revised 08/29/06